Israeli study finds antibiotics can reverse salmonella damage to stem cells in mice

An Israeli study conducted by Ben-Gurion University of the Negev researchers has demonstrated that antibiotics can fully reverse salmonella-induced damage to stem cells in mice. Using a novel mouse model that replicated chronic salmonella infection in humans, the team observed that antibiotic treatment not only led to recovery but also restored the stem cells to healthy levels. Professor Roi Gazit, who supervised the research, stated, "The experiment gives hope to people waiting for blood transplants and waiting for donors to get better." The findings, published in Cell Reports, suggest that restoring stem cell fitness before transplantation could improve clinical outcomes, potentially benefiting bone marrow transplant patients, including those over 70.